I'm so sorry to read of all the pug lives lost to PDE. We lost our Gummi almost a month ago to PDE. She was 3 years 3 months old. She never had a seizure, but she did wander off and on for a few months - she would wander for a little while, then lie down. She never pressed her head, but she was lethargic off and on. We just figured she was settling down after being a wild puppy. She woke up very lethargic one day and started wandering. I took her to the vet and she was diagnosed with pneumonia and kept in the hospital. She responded very well to the antibiotics and oxygen and I was supposed to come and see her on Friday at noon during my lunch hour. At about 9:30 am, the vet called and said she was acting odd and had a "spell" (possibly like a panicky spell, from what I gathered). They said they were keeping an eye on her. At 11:45 am I was in the bathroom before leaving for the hospital when the doctor called and left me an urgent message. She apparently was blind and was pressing her head and barely able to walk. The doctor said she was considering PDE - when I heard that message, my heart just sank. She NEVER had a seizure. By the time I drove the ten minutes to the vet (at about 90 mph), she was screaming in panic and barely able to walk - when I held her, she got more panicked. She didn't recognize me. I asked if they could sedate her so she would stop screaming so they gave her valium. I had called my daughter who was driving in from Miami. After discussing things with the doctor (who had called in three other internists and the neurologist), they were 100% sure she had PDE. My daughter got there and we spent about an hour taking turns holding her, praying with her, and playing music. We tried to get her daddy on the phone as he was out of town. Her last lucid moment was when she heard her daddy talk to her and her breathing changed and settled down. During that time, the doctor kept sedating her so she wouldn't cry out in panic or pain. We finally had her put down.
I have read that one PDE theory is that it's related to immune system problems. Gummi was born with a fierce case of demodex (which her mother apparently had - the #$&@! backyard breeders kept breeding this sick mother-we didn't know that until later). She also had, during her short time, a cardiac murmur, a small liver, kidney problems and struvite crystals and possibly stones in her bladder, a recessed vulva and vagina (which caused bladder infections). Maybe more testing can be done to check for immune system problems in pugs.
I miss Gummi every single day. She was such a spunky little girl, even with all her medical problems. I hope someday PDE will be a distant memory for the pug breed.
Mommy to Daruma Gene, the Pug of Perfection...and Roxi Lou, my sweet crazy furkid.
Always missing my sweet baby grandpug, Montgomery Marie - I will someday see you at the Rainbow Bridge, my sweet little girl - (05/25/07-08/13/10 - victim to PDE)