PDE Project Update

[Jamie]

Hi. I just wanted to update everyone on the project we are working on at Colorado State. We have nearly 20 pugs included in our study thus far (including pugs with PDE and those who passed away due to conditions other than PDE). Additionally, our radiologist who performs the MRIs here is interested in our project. At this point, we are going to start performing MRI prior to microscopic examination. Hopefully, this well help radiologists get a better idea of what PDE looks like on MRI and perhaps help with diagnosis. We are also hoping to encourage the neurologists to get involved and perhaps we can figure out a way to defer costs for patients coming to CSU for a neurologic work-up (though that is not anywhere near a done deal and may never be.....but we can hope). Anyway, I want to thank everyone for your support. I know I don't post much but I always read most of the posts to keep up-to-date with how everyone is doing. I wish I had more time to post in addition to read.....Again, thanks again to everyone, and please feel free to contact me at any time.

[TxAllieGrl]

Hi Jamie,

Thanks for the update! And thanks to you and your team for the invaluable research and work you are doing around this horrible condition. I hope that what you learn can help pug owners down the road.

And know that even when we don't hear from you, you & your team are in our thoughts.

Keep up the great work!

[ViralMD]

Jamie, what kind of microscopic exams are you doing - I'm assuming usual Nissl-staining and possibly Golgi staining and myelin staining - but is anyone doing morphometry of target areas of the brain (of course, that's assuming you can find a target and that, as a global phenomenon, the problem is possibly limited to one anatomic or functional region of the CNS)? Just asking, as an old-time neuroanatomist...Great progress so far!

[Co-Pilot in Flight]

Just another thank you to you Jamie and the team you work with. Thank you ,thank you!

[FourteenLegs]

Jamie, just knowing that you are there working away is a great comfort. Every day you and your colleagues walk in the door of your offices, is another step closer to answers. And we know you are ready, willing and able to talk with anyone who needs you. Thank you.

[SusieandPug]

Thank you for all you and your team are doing with this much needed research!

[1stTimeMom]

Thank you Jamie for eveyrthing you do. You are often in my thoughts and I hope your research is progressing in a positive direction.

[namathsmom]

Jamie,thanks for everything you are doing.

[pegatha]

Jamie - thank you for the update. As many of you know, I am a nurse, and I am constantly amazed at how information that was first developed by vets becomes information that is useful for people as well. So for at least TWO species, we are grateful for the research you do. Peg