Alternative treatment for mast cell tumors!
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Thread: Alternative treatment for mast cell tumors!

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    shaynapug's Avatar
    shaynapug is online now Village Royalty
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    DefaultAlternative treatment for mast cell tumors!

    Posted with Permission....

    Subject: alternative treatment for cancer

    This past fall, Meeko (akc intl pr ch ukc gr ch Thundrpas Meeko of Jaybar)
    was diagnosed with mast cell cancer. it was originally
    a large what we hoped isolated tumor located on the back of her neck, which
    was removed. grade II (on a scale of I-III, III being
    metatasized) at the time, highly aggressive. while we hoped for the best,
    the vet said it would be back quickly if it had metatasized.It had. The
    first week of January, Meeko began having tumors show up on her head, neck,
    muzzle, chest, back, sides, underarms - dozens everywhere. there also
    appears to be a large hard mass under her front left shoulderblade.

    A long story, but I decided to try an experimental drug that has shown
    success in treating mast cell tumors in cell culture and other types of
    cancer in mice, called curcumin. This is the yellow in tumeric, a spice
    found in curry powder. this both cuts off the blood supply to the growing
    tumor as well as causes tumor cell death (p53 mediated apoptosis).

    The dosage we started with was 80 mg/kg/day, or 400 mg twice a day for a 25
    lb dog., administered orally. The drug is available
    over the counter through health food stores and is labeled "tumeric".

    At 8 days, most of the tumors turned black, clotted, and disappeared. The
    large mass changed consistency. Unfortunately, at 10 days it was clear that
    some tumors had not been killed. We have now increased the dosage to 120
    mg/day, which is the highest we can go without toxicity.

    The drug has no apparent side affects - eating is good, she is actually
    feeling much better, the limp in the front left leg is
    gone and she is again climbing stairs. We can remove the small tumors on
    the body, IF the big ones are killed.....

    I will keep you posted. However, the important news is that the folks at
    Emory Medical School are planning a study to test
    another compound, a curcumin that has been modified so more is absorbed
    orally, in dogs with mast cell cancer, based on the results in Meeko. This
    technology is being developed by a small start up company called Curry
    Pharmaceuticals.

    Anyone interested should contact Dr. Jack Arbiser at Emory (I will forward
    contact information directly for those interested).

    PLEASE SHARE WITH ALL DOG EMAIL LISTS! YOU MAY SAVE A LIFE.

    Anne
    Dr. Camelia Anne Bishop
    http://www.myamericaneskimodogs.com
    http://www.myamericaneskimodogs.com/> __._,_.___
    Diane
    Shayna Pugs
    http://www.midmichiganpugclub.com
    Chairperson of PDCA Rescue Committee

  2. #2
    FourteenLegs is offline Village Diva
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    That is interesting, but I would like to see studies before I get excited. I will pass it on to my vets. Thanks for the info.
    Check out the PugVillage Books - buy one from HERE and help rescue.

    Rona and the Principessas Imogen and Pearl. Holding in our hearts forever LouLou and Puck who have been reunited at the Bridge.
    All my babies at the Bridge - LouLou, Puck, Piaff, Donato, Persia, Dragon, Smugs, (Pugs) and Madam and her son Woolfie (horses).

    301.9

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    shaynapug's Avatar
    shaynapug is online now Village Royalty
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    Here's another one sent to me by someone that read that article that I forwarded:

    It's too long to post here. It's by: and I'll email it to anyone interested! Will be home later on Monday.

    Medicine Chest in a Bottle?
    By
    Susan Thorpe-Vargas Ph.D






    Diane
    Shayna Pugs
    http://www.midmichiganpugclub.com
    Chairperson of PDCA Rescue Committee

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    7PugstoLove's Avatar
    7PugstoLove is offline Village Governor
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    WOW - that is amazing news...please keep us posted about the increased dosage!!! Prayers are with you.
    April - Pug Mom to Maggie, Opus, Napa, Savannah and Oliver!...and our sweet "Shillelagh" and "Haddie Bear" who play at the bridge and wait for us. Our hearts are forever blessed by them.

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    never2manypugs's Avatar
    never2manypugs is offline Village Royalty
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    Interesting...I wonder what the studies will show.
    Pam - owned by Roxie (almost 12 yrs) , Lola (14 yrs), and Olivia (almost 9 yrs)

    And Taylor, who showed me how to be loved by a pug,waits at the bridge. Mommy loves you! You will forever be in my heart.
    And never to forget, the sweetest pug ever Tasha who is at the bridge with her sister.
    And very sadly now, my baby boy Boris.

    Love is to wake up cuddling a pug.

    There are many things in life that will catch your eye, but only a few will catch your heart...pursue those.
    -- Author Unknown

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    Pugpillow's Avatar
    Pugpillow is offline Village Royalty
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    Thanks for sharing that.
    "You cannot afford to subject your animals, or your children, to medical interventions that you do not understand. The belief system upon which the conventional medical model is founded is so faulty, so corrupt and so dangerous that you simply cannot afford to follow blindly." Catherine O’Driscoll http://www.whale.to/vaccine/driscoll1.html

    Hilary & the Pugpillow Gang: Rescues: Denver (10), Tina (7), Murdoch (5) and chihuahua puppy Maximus Spartacus. Always loving my angel-girl Mei-Ling (1994-2009), my cutie-patootie Kim-Soo (1995-2010), my precious Daisy-Bo (1998?-2006), my sweet boyfriend Jake (1997-2010), my little black beauty Betsy (1995-2010), my sweet old grumpy man Gooey (1996-2011), and my sweet gentleman Farnsworth (1998-2012) at the Bridge.

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    Eliettesmom's Avatar
    Eliettesmom is offline Village Royal Pug Lip Kissin Mama
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    HMM The Cinese Herb powder I got from Mary for Earl is the color of cumin. Interesting.
    http://www.pugvillage.com/forum/private.php?do=newpm&pmid=98102The Royal Pugs. Ellie Chance & Earl


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    ViralMD is offline None
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    Again, controlled clinical trials are needed, as well as clinical pharmacology studies to determine dose, adverse effects, and pharmacokinetics. And that doesn't even count the tox studies...The time span for this? Usually, sad to say, is years....
    Viralmd, Cyril (aka Aljac Captain Hook CGC) and Tassie, the rescue chihuahua

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    Ron F is offline New to the Village
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    So I see this is a very old post....can anyone give me information on the information in the post? Just found out our 11 yo pug has mast cell....minimumal in his lymphnodes but aggressive in his groin area.....they said it was a class II but then when we met with the radiologist he felt because of the size and agressiveness it outlook would be more like for a low class III....obviously devastated!

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    bnwebm is offline Village VP
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    Lisa is pretty adept at this kind of stuff, and suggests Tagamet and Benadryl I believe. Her screenname is 6 Beautiful Pugs.

    Quote Originally Posted by Ron F View Post
    So I see this is a very old post....can anyone give me information on the information in the post? Just found out our 11 yo pug has mast cell....minimumal in his lymphnodes but aggressive in his groin area.....they said it was a class II but then when we met with the radiologist he felt because of the size and agressiveness it outlook would be more like for a low class III....obviously devastated!

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